Details

Autor(en) / Beteiligte

• Liu, De-Xian
• Li, Fei-Long
• Li, Hong-Xi
• Gong, Wei-Jie
• Gao, Jun
• Lang, Jian-Ping

Titel

Efficient and Reusable CuI/1,10-Phenanthroline-Catalyzed Oxidative Decarboxylative Homocoupling of Arylpropiolic Acids in Aqueous DMF

Ist Teil von

• European journal of organic chemistry, 2014-08, Vol.2014 (22), p.4817-4822

Ort / Verlag

Weinheim: WILEY-VCH Verlag

Erscheinungsjahr

2014

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• An efficient method for synthesis of 1,3‐diynes through the CuI/1,10‐phenanthroline‐catalyzed oxidative decarboxylative homocoupling of aryl pioprolic acids in aqueous DMF has been developed. The catalytic system was suitable for a variety of arylpropiolic acids, and the corresponding 1,3‐diynes could be prepared in high yields. The catalytic system was recovered from the organic products by filtration and its aqueous DMF filtrate retained good activity even after at least four cycles of use. A CuI/1,10‐phenanthroline system was employed to catalyze the oxidative decarboxylative homocoupling of arylpropiolic acids in aqueous DMF using air as an oxidant, producing 1,3‐diynes in good to high yields. Such a catalytic system could be reused several times.