Details

Autor(en) / Beteiligte

• Campo, Paloma, MD
• Aranda, Ana, BS
• Palacin, Arantxa, PhD
• Montañez, Maria Isabel, PhD
• Díaz-Perales, Araceli, PhD
• Blanca, Miguel, MD, PhD

Titel

Occupational asthma caused by IgE-mediated sensitization to multiple woods

Ist Teil von

• Journal of allergy and clinical immunology, 2012-01, Vol.129 (1), p.254-256.e2

Ort / Verlag

New York, NY: Mosby, Inc

Erscheinungsjahr

2012

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• All responses were immediate (30-45 minutes) except for obeche wood (90 minutes), which caused a significant proportional increase in sputum eosinophils (4.5% vs 16.9%) and a decrease in neutrophils (89.6% vs 59.5%) after challenge. Since a multiple sensitization was demonstrated, the possible cross-reactivity between woods was further analyzed by ELISA cross-inhibition assays (see this article's Online Repository at www.jacionline.org). [...]when iroko was used as solid phase, we observed that once again pine acts as a potent inhibitor (90% inhibition), followed by a more modest although significant inhibition by obeche (64%) and cerejeira (62%).