UNIVERSI
TÄ
TS-
BIBLIOTHEK
P
ADERBORN
Anmelden
Menü
Menü
Start
Hilfe
Blog
Weitere Dienste
Neuerwerbungslisten
Fachsystematik Bücher
Erwerbungsvorschlag
Bestellung aus dem Magazin
Fernleihe
Einstellungen
Sprache
Deutsch
Deutsch
Englisch
Farbschema
Hell
Dunkel
Automatisch
Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist
gegebenenfalls
nur via VPN oder Shibboleth (DFN-AAI) möglich.
mehr Informationen...
Universitätsbibliothek
Katalog
Suche
Details
Zur Ergebnisliste
Ergebnis 9 von 38085
Datensatz exportieren als...
BibTeX
Toxicity of four sulfonamide antibiotics to the freshwater amphipod Hyalella azteca
Environmental toxicology and chemistry, 2013-04, Vol.32 (4), p.866-875
Bartlett, Adrienne J.
Balakrishnan, V.K.
Toito, J.
Brown, L.R.
2013
Details
Autor(en) / Beteiligte
Bartlett, Adrienne J.
Balakrishnan, V.K.
Toito, J.
Brown, L.R.
Titel
Toxicity of four sulfonamide antibiotics to the freshwater amphipod Hyalella azteca
Ist Teil von
Environmental toxicology and chemistry, 2013-04, Vol.32 (4), p.866-875
Ort / Verlag
Hoboken, USA: John Wiley & Sons, Inc
Erscheinungsjahr
2013
Link zum Volltext
Quelle
MEDLINE
Beschreibungen/Notizen
Sulfonamides are a widely used class of antibiotics; however, there are few toxicological data available with which to conduct environmental risk assessments for these compounds. Therefore, the toxicity of four sulfonamides (sulfaguanidine, sulfathiazole, sulfamerazine, and sulfasalazine) to Hyalella azteca was assessed in chronic (four‐week), water‐only exposures. Survival was evaluated weekly, and growth was measured at the end of the test. Four‐week lethal concentrations associated with 50% mortality (LC50s) for sulfaguanidine, sulfathiazole, and sulfamerazine were 0.90, 1.6, and 3.9 µM, respectively. Sulfaguanidine caused effects on survival more quickly and at lower concentrations than sulfathiazole or sulfamerazine. These differences were more pronounced at week 1 than week 4, when sulfaguanidine LC50s were 8 to 20 times lower and 2 to 4 times lower, respectively. Growth was affected by sulfathiazole but was a less sensitive end point than survival, with an effective concentration associated with 50% reduction in growth (EC50) of 13 µM, whereas sulfaguanidine and sulfamerazine caused negligible effects on growth. Sulfasalazine had no effect on survival or growth at any concentration tested, up to 13 µM. The effects observed in the present study occurred at concentrations exceeding those typically found in environmental waters. However, given that LC50s decreased with exposure duration (except for sulfasalazine), the present study demonstrates the importance of conducting longer‐term tests to adequately assess the environmental toxicity of sulfonamides. Environ. Toxicol. Chem. 2013;32:866–875. © 2013 SETAC
Sprache
Englisch
Identifikatoren
ISSN: 0730-7268
eISSN: 1552-8618
DOI: 10.1002/etc.2129
Titel-ID: cdi_proquest_journals_1318932868
Format
–
Schlagworte
Amphipoda
,
Animal and plant ecology
,
Animal, plant and microbial ecology
,
Animals
,
Anti-Bacterial Agents - toxicity
,
Antibiotics
,
Applied ecology
,
Biological and medical sciences
,
Chronic toxicity
,
Crustacea
,
Crustaceans
,
Ecotoxicology, biological effects of pollution
,
Fresh Water - chemistry
,
Fresh water ecosystems
,
Fundamental and applied biological sciences. Psychology
,
General aspects
,
Hyalella azteca
,
Invertebrates
,
Lethal Dose 50
,
Pharmaceutical
,
Risk assessment
,
Sulfonamide antibiotic
,
Sulfonamides - toxicity
,
Synecology
,
Toxicity
,
Toxicology
,
Water Pollutants, Chemical - toxicity
Weiterführende Literatur
Empfehlungen zum selben Thema automatisch vorgeschlagen von
bX