Details

Autor(en) / Beteiligte

• Raffa, Robert B
• Amantea, Diana
• Raffa, Robert B.

Titel

Naturally Occurring Benzodiazepines, Endozepines, and their Receptors: Implications for Benzodiazepine Therapy and Withdrawal

Auflage

1

Ort / Verlag

Milton: CRC Press

Erscheinungsjahr

2022

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Understanding and addressing the current opioid crisis requires knowledge of endogenous opioids (endorphins and enkephalins), but there is now evidence for a benzodiazepine crisis. Are there endogenous benzodiazepine-like substances-and what do they do? How do they affect the antianxiety drugs and their adverse effects? Do they explain the enigmatic prolonged benzodiazepine withdrawal syndrome? Naturally Occurring Benzodiazepines, Endozepines, and their Receptors: Implications for Benzodiazepine Therapy and Withdrawal raises important questions about the clinical consequences of ignoring the existence of or understanding the potential influence of endogenous benzodiazepines on the therapeutic effect of benzodiazepines, their adverse effects, and the problems of withdrawal from them and other benzodiazepine receptor agonists. Key Features: Discusses endogenous benzodiazepine-like substances-what do they do, and do they affect the antianxiety drugs and their adverse effects? Presents information on the enigmatic prolonged benzodiazepine withdrawal syndrome Describes the compounds acting at the BDZ binding sites, both exogenous (classical BDZ drugs and BDZ from food and plants) and endogenous (endozepines) Assesses the putative interactions in physiology, pathology, and pharmacology of the compounds acting at the BDZ binding sites