Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (51), p.20063-20066
2008
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Details
- Autor(en) / Beteiligte
- Titel
- Properties of developmental gene regulatory networks
- Ist Teil von
- Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (51), p.20063-20066
- Ort / Verlag
- United States: National Academy of Sciences
- Erscheinungsjahr
- 2008
- Quelle
- EZB-FREE-00999 freely available EZB journals
- Beschreibungen/Notizen
- The modular components, or subcircuits, of developmental gene regulatory networks (GRNs) execute specific developmental functions, such as the specification of cell identity. We survey examples of such subcircuits and relate their structures to corresponding developmental functions. These relations transcend organisms and genes, as illustrated by the similar structures of the subcircuits controlling the specification of the mesectoderm in the Drosophila embryo and the endomesoderm in the sea urchin, even though the respective subcircuits are composed of nonorthologous regulatory genes.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0027-8424eISSN: 1091-6490DOI: 10.1073/pnas.0806007105Titel-ID: cdi_pnas_primary_105_51_20063
- Format
- –
- Schlagworte
- Animals, Cells, Crustaceans, Drosophila, Echinoidea, Ectoderm, Ectoderm - cytology, Ectoderm - embryology, Electrical circuits, Embryo, Nonmammalian, Embryonic Development, Embryos, Evolution, Gene Networks in Development and Evolution Special Feature Sackler Colloquium, Gene Regulatory Networks - physiology, Genes, Genetics, Government regulation, Growth and Development - genetics, Insects, Ligands, Mesoderm, Mesoderm - cytology, Mesoderm - embryology, Sea Urchins, Signal Transduction, Transcription Factors