Details

Autor(en) / Beteiligte

• Singh, Arti
• Arulogun, Oyedunni
• Akinyemi, Joshua
• Nichols, Michelle
• Calys-Tagoe, Benedict
• Ojebuyi, Babatunde
• Jenkins, Carolyn
• Obiako, Reginald
• Akpalu, Albert
• Sarfo, Fred
• Wahab, Kolawole
• Sunday, Adeniyi
• Owolabi, Lukman F
• Adigun, Muyiwa
• Afolami, Ibukun
• Olorunsogbon, Olorunyomi
• Ogunronbi, Mayowa
• Melikam, Ezinne Sylvia
• Laryea, Ruth
• Asibey, Shadrack
• Oguike, Wisdom
• Melikam, Lois
• Sule, Abdullateef
• Titiloye, Musibau A
• Yahaya, Isah Suleiman
• Bello, Abiodun
• Kalaria, Rajesh N
• Jegede, Ayodele
• Owolabi, Mayowa
• Ovbiagele, Bruce
• Akinyemi, Rufus
• Kuivaniemi, Helena

Titel

Biological sample donation and informed consent for neurobiobanking: Evidence from a community survey in Ghana and Nigeria

Ist Teil von

• PloS one, 2022-08, Vol.17 (8), p.e0267705-e0267705

Ort / Verlag

San Francisco: Public Library of Science

Erscheinungsjahr

2022

Link zum Volltext

Quelle

EZB Free E-Journals

Beschreibungen/Notizen

• Introduction Genomic research and neurobiobanking are expanding globally. Empirical evidence on the level of awareness and willingness to donate/share biological samples towards the expansion of neurobiobanking in sub-Saharan Africa is lacking. Aims To ascertain the awareness, perspectives and predictors regarding biological sample donation, sharing and informed consent preferences among community members in Ghana and Nigeria. Methods A questionnaire cross-sectional survey was conducted among randomly selected community members from seven communities in Ghana and Nigeria. Results Of the 1015 respondents with mean age 39.3 years (SD 19.5), about a third had heard of blood donation (37.2%, M: 42.4%, F: 32.0%, p = 0.001) and a quarter were aware of blood sample storage for research (24.5%; M: 29.7%, F: 19.4%, p = 0.151). Two out of ten were willing to donate brain after death (18.8%, M: 22.6%, F: 15.0%, p<0.001). Main reasons for unwillingness to donate brain were; to go back to God complete (46.6%) and lack of knowledge related to brain donation (32.7%). Only a third of the participants were aware of informed consent (31.7%; M: 35.9%, F: 27.5%, p<0.001). Predictors of positive attitude towards biobanking and informed consent were being married, tertiary level education, student status, and belonging to select ethnic groups. Conclusion There is a greater need for research attention in the area of brain banking and informed consent. Improved context-sensitive public education on neurobiobanking and informed consent, in line with the sociocultural diversities, is recommended within the African sub region.