Details

Autor(en) / Beteiligte

• Lim, Zhu Wei
• Wang, I-Duo
• Wang, Panchalli
• Chung, Chi-Hsiang
• Huang, Song-Shan
• Huang, Chien-Chu
• Tsai, Pei-Yi
• Wu, Gwo-Jang
• Wu, Kuo-Hsiang
• Chien, Wu-Chien
• Rowley, James Andrew

Titel

Obstructive sleep apnea increases risk of female infertility: A 14-year nationwide population-based study

Ist Teil von

• PloS one, 2021-12, Vol.16 (12), p.e0260842

Ort / Verlag

United States: Public Library of Science

Erscheinungsjahr

2021

Quelle

MEDLINE

Beschreibungen/Notizen

• To determine the risk of having OSA in a cohort of female subjects who are infertile and the odds of being infertile in women with OSA. A nationwide, case-control study of female patients 20 years or older diagnosed with female infertility living in Taiwan, from January 1, 2000, through December 31, 2013 (N = 4,078). We identified women who were infertile and created a 2:1 matched control group with women who were not infertile. We used multivariable logistic regression analysis to further estimate the effects of OSA on female infertility. In this 14- year retrospective study, we included 4,078 patients having an initial diagnosis of female infertility. Of those women with infertility, 1.38% had a history of OSA compared with 0.63% of fertile controls (p = 0.002). The mean ages in the study groups were 32.19 ± 6.20 years, whereas the mean ages in the control groups were 32.24 ± 6.37years. Women with OSA had 2.101- times the risk of female infertility compared to women without OSA (p<0.001). Our study showed that OSA is more commonly seen in infertile women and increases the odds that a woman will be infertile. More studies need to be done on the whether or not diagnosing and treating OSA can decrease the rate of infertility.