Details

Autor(en) / Beteiligte

• Coventry, Peter A.
• Meader, Nick
• Melton, Hollie
• Temple, Melanie
• Dale, Holly
• Wright, Kath
• Cloitre, Marylène
• Karatzias, Thanos
• Bisson, Jonathan
• Roberts, Neil P.
• Brown, Jennifer V. E.
• Barbui, Corrado
• Churchill, Rachel
• Lovell, Karina
• McMillan, Dean
• Gilbody, Simon
• Bendall, Sarah

Titel

Psychological and pharmacological interventions for posttraumatic stress disorder and comorbid mental health problems following complex traumatic events: Systematic review and component network meta-analysis

Ist Teil von

• PLoS medicine, 2020-08, Vol.17 (8), p.e1003262-e1003262

Ort / Verlag

San Francisco: Public Library of Science

Erscheinungsjahr

2020

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Furthermore, we still do not know which treatment components are most effective and acceptable for people with PTSD following complex-trauma histories. Because of the narrow analytical focus and limitations of the current evidence base, we conducted a systematic review to identify and integrate all direct and indirect comparisons of psychological and pharmacological treatments versus usual care and active controls in treating mental health problems in people with a history of complex traumatic events. Secondary outcomes were reductions in symptoms of disturbances of self-organisation (affect dysregulation; negative self-concept; disturbances in relationships); reduction in symptoms of depression and anxiety, dissociation, functional somatic syndromes; acceptability (attrition); adverse events and harms from trial data (e.g., worsening of traumatic stress symptoms); suicidal ideation, attempts, and completion; and quality of life measured by validated clinician-rated scales. Search strategy and selection criteria Literature searches were initially conducted in April 2017 in these databases: CINAHL, Cochrane Central Register of Controlled Trials (CENTRAL), Embase, International Pharmaceutical Abstracts, MEDLINE, Published International Literature on Traumatic Stress (PILOTS), PsycINFO, and Science Citation Index. [...]update searches using the MEDLINE and PsycINFO databases were carried out in October 2019.