Details

Autor(en) / Beteiligte

• Fransen, Heidi P
• May, Anne M
• Beulens, Joline W J
• Struijk, Ellen A
• de Wit, G Ardine
• Boer, Jolanda M A
• Onland-Moret, N Charlotte
• Hoekstra, Jeljer
• van der Schouw, Yvonne T
• Bueno-de-Mesquita, H Bas
• Peeters, Petra H M
• Lee, Jung Eun

Titel

Association between lifestyle factors and quality-adjusted life years in the EPIC-NL cohort

Ist Teil von

• PloS one, 2014-11, Vol.9 (11), p.e111480-e111480

Ort / Verlag

United States: Public Library of Science

Erscheinungsjahr

2014

Quelle

MEDLINE

Beschreibungen/Notizen

• The aim of our study was to relate four modifiable lifestyle factors (smoking status, body mass index, physical activity and diet) to health expectancy, using quality-adjusted life years (QALYs) in a prospective cohort study. Data of the prospective EPIC-NL study were used, including 33,066 healthy men and women aged 20-70 years at baseline (1993-7), followed until 31-12-2007 for occurrence of disease and death. Smoking status, body mass index, physical activity and adherence to a Mediterranean-style diet (excluding alcohol) were investigated separately and combined into a healthy lifestyle score, ranging from 0 to 4. QALYs were used as summary measure of healthy life expectancy, combining a person's life expectancy with a weight for quality of life when having a chronic disease. For lifestyle factors analyzed separately the number of years living longer in good health varied from 0.12 year to 0.84 year, after adjusting for covariates. A combination of the four lifestyle factors was positively associated with higher QALYs (P-trend <0.0001). A healthy lifestyle score of 4 compared to a score of 0 was associated with almost a 2 years longer life in good health (1.75 QALYs [95% CI 1.37, 2.14]).