PloS one, 2012-02, Vol.7 (2), p.e32096-e32096
2012
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Details
- Autor(en) / Beteiligte
- Titel
- Identification of cancer cell-line origins using fluorescence image-based phenomic screening
- Ist Teil von
- PloS one, 2012-02, Vol.7 (2), p.e32096-e32096
- Ort / Verlag
- United States: Public Library of Science
- Erscheinungsjahr
- 2012
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Universal phenotyping techniques that can discriminate among various states of biological systems have great potential. We applied 557 fluorescent library compounds to NCI's 60 human cancer cell-lines (NCI-60) to generate a systematic fluorescence phenotypic profiling data. By the kinetic fluorescence intensity analysis, we successfully discriminated the organ origin of all the 60 cell-lines.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1932-6203eISSN: 1932-6203DOI: 10.1371/journal.pone.0032096Titel-ID: cdi_plos_journals_1323859542
- Format
- –
- Schlagworte
- Algorithms, Apoptosis, Biology, Boron Compounds - pharmacology, Cancer, Cell cycle, Cell Line, Tumor, Chemistry, Cluster Analysis, Colorectal cancer, Consortia, Fluorescence, Fluorescent Dyes - chemistry, Gene expression, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Genetic aspects, Genomics, Genotype & phenotype, Humans, Kidney cancer, Kinetics, Library collections, Life sciences, Medical screening, Medicine, MicroRNAs, Microscopy, Fluorescence - methods, Organic Chemicals - pharmacology, Phenotype, Phenotyping, Rodents