Details

Autor(en) / Beteiligte

• Mackenzie, Grant A
• Plumb, Ian D
• Sambou, Sana
• Saha, Debasish
• Uchendu, Uchendu
• Akinsola, Bolanle
• Ikumapayi, Usman N
• Baldeh, Ignatius
• Usuf, Effua
• Touray, Kebba
• Jasseh, Momodou
• Howie, Stephen R C
• Wattiaux, Andre
• Lee, Ellen
• Knoll, Maria Deloria
• Levine, Orin S
• Greenwood, Brian M
• Adegbola, Richard A
• Hill, Philip C

Titel

Monitoring the introduction of pneumococcal conjugate vaccines into West Africa: design and implementation of a population-based surveillance system

Ist Teil von

• PLoS medicine, 2012-01, Vol.9 (1), p.e1001161-e1001161

Ort / Verlag

United States: Public Library of Science

Erscheinungsjahr

2012

Quelle

MEDLINE

Beschreibungen/Notizen

• Routine use of pneumococcal conjugate vaccines (PCVs) in developing countries is expected to lead to a significant reduction in childhood deaths. However, PCVs have been associated with replacement disease with non-vaccine serotypes. We established a population-based surveillance system to document the direct and indirect impact of PCVs on the incidence of invasive pneumococcal disease (IPD) and radiological pneumonia in those aged 2 months and older in The Gambia, and to monitor changes in serotype-specific IPD. Here we describe how this surveillance system was set up and is being operated as a partnership between the Medical Research Council Unit and the Gambian Government. This surveillance system is expected to provide crucial information for immunisation policy and serves as a potential model for those introducing routine PCV vaccination in diverse settings.