Details

Autor(en) / Beteiligte

• Lundeen, Jeffrey T.
• Juvet, Richard S.

Titel

Quantitative resolution of severely overlapping gas chromatographic peaks : Isothermal and temperature-programmed operation

Ist Teil von

• Journal of Chromatography A, 1991-09, Vol.556 (1), p.305-316

Ort / Verlag

Amsterdam: Elsevier B.V

Erscheinungsjahr

1991

Quelle

Access via ScienceDirect (Elsevier)

Beschreibungen/Notizen

• Severely overlapping gas chromatographic peaks ( R -⩽ 0.35) are quantitatively resolved by a mathematical method. Accurate analyses may be obtained under the worst of overlapping conditions even with simple chromatographic instrumentation. For the method to be successful either the peak shapes of each component must differ if the retention times are identical, or their retention times must be slightly different if the peak shapes are identical. The method has been tested on both isothermal and temperature-programmed data. The computer method proposed requires correction for fluctuations in carrier gas flow-rate and programmed column temperature, both of which cause irreproducibility in peak position. A procedure for accomplishing this correction is presented.