International journal of radiation biology, 1996, Vol.69 (4), p.481-485
1996
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Details
- Autor(en) / Beteiligte
- Titel
- Repair of dGMP hydroxyl radical adducts by verbascoside via electron transfer: a pulse radiolysis study
- Ist Teil von
- International journal of radiation biology, 1996, Vol.69 (4), p.481-485
- Ort / Verlag
- London: Informa UK Ltd
- Erscheinungsjahr
- 1996
- Quelle
- Taylor & Francis
- Beschreibungen/Notizen
- The repair activity of verbascoside (VER), isolated from Pedicularis spicata, towards the oxidizing hydroxyl radical adduct of dGMP and its reaction mechanism were studied using pulse radiolysis. Upon pulse radiolysis of nitrous oxide saturated aqueous solution of 2-deoxyguanosine-5-monophosphate (dGMP) and VER, it was found that the transient absorption spectrum of the hydroxyl adduct of dGMP decays with the formation of that of the phenoxyl radical of VER, several tens of microseconds after the electron pulse. From the formation kinetics of the phenoxyl radical of VER, the rate constant of the repair reaction was determined to be 1. 12 109 dm3 mol- 1 s- 1.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0955-3002eISSN: 1362-3095DOI: 10.1080/095530096145779Titel-ID: cdi_pascalfrancis_primary_3092064
- Format
- –
- Schlagworte
- Antioxidants - pharmacology, Applied radiobiology (equipment, dosimetry...), Biological and medical sciences, Biological effects of radiation, Deoxyguanine Nucleotides - metabolism, DNA Repair, Fundamental and applied biological sciences. Psychology, Glucosides - pharmacology, Hydroxyl Radical, Phenols, Pulse Radiolysis, Space life sciences, Tissues, organs and organisms biophysics