Details

Autor(en) / Beteiligte

• Redou, Pascal
• Kerdelo, Sébastien
• Le Gal, Christophe
• Querrec, Gabriel
• Rodin, Vincent
• Abgrall, Jean-François
• Tisseau, Jacques
• Dias, Gaël
• Cardoso, Amílcar
• Bento, Carlos

Titel

Reaction-Agents: First Mathematical Validation of a Multi-agent System for Dynamical Biochemical Kinetics

Ist Teil von

• Lecture notes in computer science, 2005, p.156-166

Ort / Verlag

Berlin, Heidelberg: Springer Berlin Heidelberg

Erscheinungsjahr

2005

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• In the context of multi-agent simulation of biological complex systems, we present a reaction-agent model for biological chemical kinetics that enables interaction with the simulation during the execution. In a chemical reactor with no spatial dimension -e.g. a cell-, a reaction-agent represents an autonomous chemical reaction between several reactants : it reads the concentration of reactants, adapts its reaction speed, and modifies consequently the concentration of reaction products. This approach, where the simulation engine makes agents intervene in a chaotic and asynchronous way, is an alternative to the classical model -which is not relevant when the limits conditions change- based on differential systems. We establish formal proofs of convergence for our reaction-agent methods, generally quadratic. We illustrate our model with an example about the extrinsic pathway of blood coagulation.