A charge-modulated FET for detection of biomolecular processes: conception, modeling, and simulation
2006
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- Autor(en) / Beteiligte
- Titel
- A charge-modulated FET for detection of biomolecular processes: conception, modeling, and simulation
- Ist Teil von
- IEEE transactions on electron devices, 2006-01, Vol.53 (1), p.158-166
- Ort / Verlag
- New York, NY: IEEE
- Erscheinungsjahr
- 2006
- Quelle
- IEEE/IET Electronic Library (IEL)
- Beschreibungen/Notizen
- A novel, solid-state sensor for charge detection in biomolecular processes is proposed. The device, called charge-modulated field-effect transistor, is compatible with a standard CMOS process, thus allowing fully electronic readout and large scale of integration of biosensors on a single chip. The detection mechanism is based on the field-effect modulation induced by electric charge changes related to the bioprocess. A model of the device was developed, to provide a manageable relationship between its output and geometric, design and process parameters. Extensive two- and three-dimensional simulations of the proposed structure validated the model and the working principle.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0018-9383eISSN: 1557-9646DOI: 10.1109/TED.2005.860659Titel-ID: cdi_pascalfrancis_primary_17389823
- Format
- –
- Schlagworte
- Applied sciences, Biological and medical sciences, Biomedical transducers, Biosensors, Biotechnology, Charge sensor, CMOS, CMOS integrated circuits, Compatibility, Computer simulation, Design. Technologies. Operation analysis. Testing, Devices, DNA, DNA detection, DNA-chip, Electric charge, Electronics, Exact sciences and technology, field-effect transistor (FET) sensor, Fundamental and applied biological sciences. Psychology, General equipment and techniques, Instruments, apparatus, components and techniques common to several branches of physics and astronomy, Integrated circuits, Methods. Procedures. Technologies, micro-arrays, Modulation, Molecular electronics, MOSFETs, Physics, Semiconductor electronics. Microelectronics. Optoelectronics. Solid state devices, Sensors (chemical, optical, electrical, movement, gas, etc.), remote sensing, Transistors, Various methods and equipments