Details

Autor(en) / Beteiligte

• Hong, M.H. (Sejong University, Seoul, Republic of Korea)
• Choe, Y.H. (Sungkyunkwan University, Seoul, Republic of Korea)
• Cho, Y.J. (EyeGene Inc., Seoul, Republic of Korea)
• Ahn, B.Y. (EyeGene Inc., Seoul, Republic of Korea)
• Lee, N.G. (Sejong University, Seoul, Republic of Korea), E-mail: nglee@sejong.ac.kr

Titel

Sequencing and Comparative Analysis of napA Genes from Helicobacter pylori Strains Associated with Iron-Deficiency Anemia

Ist Teil von

• Journal of microbiology and biotechnology, 2005-08, Vol.15 (4), p.866-872

Ort / Verlag

Seoul: Korean Society for Applied Microbiology

Erscheinungsjahr

2005

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• H. pylori is known to cause severe gastric diseases, including peptic ulcers and gastric cancers, and a link has also been suggested with iron-deficiency anemia (IDA). However, little is known about the pathogenesis of H. pylori-associated IDA. In the present study, to determine whether H. pylori strains are correlated with the prevalence of IDA, we analyzed and compared the sequences of the napA genes encoding a bacterioferritin-like protein in H. pylori strains. A total of 20 H. pylori strains were isolated from antral biopsies of patients with and without IDA, and the napA genes amplified from the genomic DNA were sequenced.