Details

Autor(en) / Beteiligte

• Anderson, Harry L
• Hunter, Christopher A
• Meah, M. Nafees
• Sanders, Jeremy K. M

Titel

Thermodynamics of induced-fit binding inside polymacrocyclic porphyrin hosts

Ist Teil von

• Journal of the American Chemical Society, 1990-07, Vol.112 (15), p.5780-5789

Ort / Verlag

Washington, DC: American Chemical Society

Erscheinungsjahr

1990

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The binding of bis-amine ligands to a series of cyclic zinc porphyrin dimers has been characterized by NMR and electronic spectroscopy. The cavity within the flexible dimers is kept closed by {pi}-{pi} interactions between the porphyrin and aromatic bridging groups but can be opened by ligands whose binding is strong enough to overcome this energetic barrier. Analysis of the binding of these bifunctional and the corresponding monofunctional ligands to the porphyrin dimers and corresponding monomeric porphyrins allowed definition of the parameters {Delta}{Delta}G, {Delta}{Delta}H, and {Delta}{Delta}S. These are specifically associated with the energetic costs of conformational switching and yield information about the strength of the {pi}-{pi} interactions that hold the cavity closed.