Details
- Autor(en) / Beteiligte
- Titel
- Recent Progress in Solid Dispersion Technology
- Ort / Verlag
- MDPI
- Erscheinungsjahr
- 2019
- Link zum Volltext
- Quelle
- Alma/SFX Local Collection
- Beschreibungen/Notizen
- Amorphous solid dispersion (ASD) is a powerful formulation technology to improve oral absorption of poorly soluble drugs. Despite their being in existence for more than half a century, controlling ASD performance is still regarded as difficult because of ASD’s natural non-equilibrium. However, recent significant advances in ASD knowledge and technology may enable a much broader use of ASD technology. This Special Issue, which includes 3 reviews and 6 original articles, focuses on recent progresses in ASD technology in hopes of helping to accelerate developmental studies in the pharmaceutical industry. In striving for a deep understanding of ASD non-equilibrium behavior, the Special issue also delves into and makes progress in the theory of soft-matter dynamics.
- Sprache
- Englisch
- Identifikatoren
- ISBN: 3039215027, 9783039215027, 3039215019, 9783039215010DOI: 10.3390/books978-3-03921-502-7Titel-ID: cdi_oapen_doabooks_57786
- Format
- –
- Schlagworte
- accelerated stability test, amorphisation, amorphous, amorphous polymeric salt, amorphous solid dispersion, amorphous solid dispersions, anticancer drugs, ball milling, bicaludamide, bioavailability, Biology, life sciences, Book Industry Communication, characterization, ciprofloxacin, classification, continuous processing, crystallization, crystallization tendency, dissolution, dissolution enhancement, dissolution rate, enrofloxacin, evaporation, granulation, hot melt extrusion, interaction, intrinsic dissolution rate, manufacturing methods, Mathematics & science, mesoporous, milling, miscibility, molecular complex, molecular dynamics simulation, nanoaggregates, nucleation, pharmaceutical glass, phase diagram, poloxamer, polyelectrolyte excipient matrix, polyelectrolytes, polymer, poorly soluble drugs, process development, rebamipide, self-assembly, solid dispersion, solid dispersions, solubility, solubility enhancement, spectroscopic techniques, spray drying, stability, tadalafil, thermal analysis, thermodynamic modeling, Weibull dissolution model, Wood’s apparatus