Details

Autor(en) / Beteiligte

• Ryoo, S.W. (Korean Institute of Tuberculosis, Seoul, Republic of Korea)
• Park, Y.K. (Korean Institute of Tuberculosis, Seoul, Republic of Korea)
• Park, S.N. (Korea Food and Drug Administration, Seoul, Republic of Korea)
• Shim, Y.S. (Seoul National University, Seoul, Republic of Korea)
• Liew, H.J. (Seoul National University, Seoul, Republic of Korea)
• Kang, S.M. (Korea University, Seoul, Republic of Korea)
• Bai, G.H. (Korean Institute of Tuberculosis, Seoul, Republic of Korea), E-mail: scientist1@empal.com

Titel

Comparative Proteomic Analysis of Virulent Korean Mycobacterium tuberculosis K-strain with Other Mycobacteria Strain Following Infection of U-937 Macrophage

Ist Teil von

• The Journal of Microbiology, 2007, 45(3), , pp.268-271

Ort / Verlag

Korea (South): 한국미생물학회

Erscheinungsjahr

2007

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• In Korea, the Mycobacterium tuberculosis K-strain is the most prevalent clinical isolates and belongs to the Beijing family. In this study, we conducted comparative porteomics of expressed proteins of clinical isolates of the K-strain with H37Rv, H37Ra as well as the vaccine strain of Mycobacterium bovis BCG following phagocytosis by the human monocytic cell line U-937. Proteins were analyzed by 2-D PAGE and MALDI-TOF-MS. Two proteins, Mb1363 (probable glycogen phosphorylase GlgP) and MT2656 (Haloalkane dehalogenase LinB) were most abundant after phagocytosis of M. tuberculosis K-strain.