Korean Journal of Ophthalmology, 2020, 34(1), , pp.46-55
2020
Details
- Autor(en) / Beteiligte
- Titel
- Effect of 0.1% Bromfenac for Preventing Macular Edema after Cataract Surgery in Patients with Diabetes
- Ist Teil von
- Korean Journal of Ophthalmology, 2020, 34(1), , pp.46-55
- Ort / Verlag
- Korea (South): The Korean Ophthalmological Society
- Erscheinungsjahr
- 2020
- Link zum Volltext
- Quelle
- EZB Electronic Journals Library
- Beschreibungen/Notizen
- To investigate the effect of 0.1% bromfenac sodium hydrate ophthalmic solution for prevention of macular edema after cataract surgery in patients with diabetes. A retrospective analysis of 75 patients with diabetes who underwent cataract surgery was performed. Thirty-eight patients (52 eyes) were instilled with 0.1% bromfenac solution (bromfenac group) and 37 patients (46 eyes) were not (control group). There were no significant preoperative between-group differences. Compared to the control group, at 1 month after surgery, the bromfenac group showed slightly better best-corrected visual acuity (0.12 ± 0.12 vs. 0.32 ± 0.42, = 0.142), lower central macular thickness (265.58 ± 31.28 vs. 314.15 ± 76.11 μm, < 0.001), and lower macular volume (8.46 ± 0.60 vs. 9.14 ± 1.53 mm³, = 0.022). There were no significant differences between the two groups at 4 and 6 months postoperatively ( > 0.05). Mean changes in central macular thickness showed significant differences at 1 and 4 months postoperatively (-1.44 ± 11.72 and 10.44 ± 22.48 μm in bromfenac group vs. 47.19 ± 70.24 and 31.69 ± 48.04 μm in control group, < 0.001 and = 0.016) and mean changes in macular volume showed a significant difference at 1 month postoperatively (-0.08 ± 0.47 mm³ in bromfenac group vs. 0.58 ± 1.28 mm³ in control group, < 0.001). There were no significant differences thereafter ( > 0.05). Treatment with 0.1% bromfenac sodium hydrate ophthalmic solution showed good efficacy for preventing cystoid macular edema early after cataract surgery in patients with diabetes.