Details

Autor(en) / Beteiligte

• Kim, Sang Gyun
• Park, Chan Mi
• Lee, Na Rae
• Kim, Jiyoung
• Lyu, Da Hyun
• Park, Seung-Hee
• Choi, Il Ju
• Lee, Wan Sik
• Park, Seun Ja
• Kim, Jae Jun
• Kim, Ji Hyun
• Lim, Chul-Hyun
• Cho, Joo Young
• Kim, Gwang Ha
• Lee, Yong Chan
• Jung, Hwoon-Yong
• Lee, Jun Haeng
• Chun, Hoon Jai
• Seol, Sang-Yong

Titel

Long-Term Clinical Outcomes of Endoscopic Submucosal Dissection in Patients with Early Gastric Cancer: A Prospective Multicenter Cohort Study

Ist Teil von

• Gut and Liver, 2018, 12(4), , pp.402-410

Ort / Verlag

Korea (South): Editorial Office of Gut and Liver

Erscheinungsjahr

2018

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Endoscopic submucosal dissection (ESD) has been regarded as a curative treatment for early gastric cancer (EGC) in indicated cases. The aim of this study was to evaluate the nationwide long-term clinical outcomes of ESD for EGC in Korea. A prospective multicenter cohort study was performed to evaluate the long-term efficacy of ESD for EGC within pre-defined indications at 12 institutes in Korea. The cases that met the expanded criteria upon pathological review after ESD were followed for 5 years. The primary outcome was 5-year disease specific free survival. Six hundred ninety-seven patients with 722 EGCs treated with ESD were prospectively enrolled and followed for 5 years. Complete resection was achieved in 81.3% of the cases, and curative resection was achieved in 86.1%. During the 5-year follow-up, the overall survival rate was 96.6%, and the disease specific free survival rate was 90.6%. Local recurrence developed in 0.9%, and metachronous tumor development occurred in 7.8%; both conditions were treated by endoscopic or surgical treatment. Distant metastasis developed in 0.5% during follow-up. ESD showed excellent long-term clinical outcomes and can be accepted as a curative treatment for patients with EGC who meet the expanded criteria in final pathology studies.