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Kiwifruit of Actinidia eriantha cv. Bidan has in vitro antioxidative, anti-inflammatory and immunomodulatory effects on macrophages and splenocytes isolated from male BALB/c mice
Ist Teil von
Food Science and Biotechnology, 2018, 27(5), , pp.1503-1511
Ort / Verlag
Singapore: Springer Singapore
Erscheinungsjahr
2018
Quelle
Alma/SFX Local Collection
Beschreibungen/Notizen
Kiwifruit is known to contain considerable amount of antioxidative phenolics. The objective of this study was to evaluate the antioxidative, anti-inflammatory and immunomodulatory effects of
Actinidia eriantha
cv. Bidan and
A. deliciosa
cv. Hayward kiwifruits. The antioxidant capacity of kiwifruit was measured with the DPPH, ABTS and ORAC assays, and was significantly (
p
< 0.05) higher in cv. Bidan than in cv. Hayward. The production of proinflammatory cytokines interleukin-6, interleukin-12 and tumor necrosis factor-α by peritoneal macrophages from male BALB/c mice was significantly (
p
< 0.05) lower following treatment of cv. Bidan extracts than after treatment with lipopolysaccharide alone. Cv. Bidan extracts significantly (
p
< 0.05) increased the proliferation of splenocytes stimulated with an anti-CD3 antibody and significantly (
p
< 0.05) reduced their interferon-γ secretion. Taken together, these findings suggest that cv. Bidan kiwifruit is rich in antioxidants and may be a source of anti-inflammatory and immunomodulatory agents.