Details

Autor(en) / Beteiligte

• Ha, Phuong T.M.
• Le, Binh T.T.
• To, Trung C.
• Doan, Son H.
• Nguyen, Tung T.
• Phan, Nam T.S.

Titel

Synthesis of aryl-substituted pyridines via cyclization of N,N-dialkylanilines with ketoxime carboxylates under metal-organic framework catalysis

Ist Teil von

• Journal of Industrial and Engineering Chemistry, 2017, 54(0), , pp.151-161

Ort / Verlag

Elsevier B.V

Erscheinungsjahr

2017

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• [Display omitted] •Fe3O(BPDC)3 was used as catalyst for synthesis of aryl-substituted pyridines.•Excellent yields were obtained.•The catalyst could be recovered and reused. Iron-organic framework Fe3O(BPDC)3 was synthesized, and subsequently utilized as an productive heterogeneous catalyst for the cyclization reaction of N,N-dialkylanilines with ketoxime carboxylates to produce aryl-substituted pyridines. This iron-organic framework catalyst demonstrated remarkably higher catalytic productivity for the synthesis of aryl-substituted pyridines as compared to numerous conventional homogeneous catalysts as well as MOF-based catalysts. It was possible to reuse the iron-framework catalyst in the cyclization transformation for numerous cycles without a noticeable decline in activity. To our best knowledge, this is the first heterogeneous catalytic approach towards the synthesis of aryl-substituted pyridines from ketoximes.