Details

Autor(en) / Beteiligte

• Lim, Dong-Jin
• Sim, Myeongbu
• Oh, Leeseul
• Lim, Kyunghee
• Park, Hansoo

Titel

Carbon-based drug delivery carriers for cancer therapy

Ist Teil von

• Archives of Pharmacal Research, 2014, 37(1), , pp.43-52

Ort / Verlag

Dordrecht: Springer Netherlands

Erscheinungsjahr

2014

Quelle

MEDLINE

Beschreibungen/Notizen

• In the search to improve anticancer therapies, several drug carriers, including carbon-based nanomaterials have been studied. Both liposomes and polymeric microspheres have been used in anticancer drugs. However, there remains an on-going need for better therapeutic materials that have good drug solubility, an ability to reduce systemic toxicity through specific-tumor targeting, and rapid clearance. In this regard, carbon allotropes such as graphene oxide (GOs), carbon nanotubes (CNTs), and nanodiamonds (NDs), have been investigated, as they possess sufficient surface-to-volume ratio, thermal conductivity, rigid structural properties capable of post-chemical modification, and excellent biocompatibility. This review is aimed at exploring these carbon-based nanomaterials for use as multifaceted cancer drug carriers and is intended to demonstrate that GOs, CNTs, and NDs are likely to improve chemotherapeutical strategy for cancers in either a sole or combinational manner.