Details

Autor(en) / Beteiligte

• Liu, Ya-Xiao
• Song, Xiao-Mei
• Dan, Lin-Wei
• Tang, Jia-Mei
• Jiang, Yi
• Deng, Chong
• Zhang, Dong-Dong
• Li, Yu-Ze
• Wang, Wei

Titel

Astragali Radix: comprehensive review of its botany, phytochemistry, pharmacology and clinical application

Ist Teil von

• Archives of Pharmacal Research, 2024, 47(3), , pp.165-218

Ort / Verlag

Seoul: Pharmaceutical Society of Korea

Erscheinungsjahr

2024

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Astragali Radix ( A. Radix ) is the dried root of Astragalus membranaceus var. mongholicus (Bge) Hsiao or Astragalus membranaceus (Fisch.) Bge., belonging to the family Leguminosae, which is mainly distributed in China. A. Radix has been consumed as a tonic in China for more than 2000 years because of its medicinal effects of invigorating the spleen and replenishing qi. Currently, more than 400 natural compounds have been isolated and identified from A. Radix , mainly including saponins, flavonoids, phenylpropanoids, alkaloids, and others. Modern pharmacological studies have shown that A. Radix has anti-tumor, anti-inflammatory, immunomodulatory, anti-atherosclerotic, cardioprotective, anti-hypertensive, and anti-aging effects. It has been clinically used in the treatment of tumors, cardiovascular diseases, and cerebrovascular complications associated with diabetes with few side effects and high safety. This paper reviewed the progress of research on its chemical constituents, pharmacological effects, clinical applications, developing applications, and toxicology, which provides a basis for the better development and utilization of A. Radix .