Details

Autor(en) / Beteiligte

• Chung, Jae Hoon
• Song, Wan
• Kang, Minyong
• Sung, Hyun Hwan
• Jeon, Hwang Gyun
• Jeong, Byong Chang
• Seo, Seong Il
• Jeon, Seong Soo
• Lee, Hyun Moo
• Park, Byung Kwan

Titel

Sextant Systematic Biopsy Versus Extended 12-Core Systematic Biopsy in Combined Biopsy for Prostate Cancer

Ist Teil von

• Journal of Korean Medical Science, 2024, 39(7), , pp.1-12

Ort / Verlag

Korea (South): The Korean Academy of Medical Sciences

Erscheinungsjahr

2024

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• This study assessed the comparative effectiveness of sextant and extended 12-core systematic biopsy within combined biopsy for the detection of prostate cancer. Patients who underwent combined biopsy targeting lesions with a Prostate Imaging Reporting and Data System (PI-RADS) score of 3-5 were assessed. Two specialists performed all combined cognitive biopsies. Both specialists performed target biopsies with five or more cores. One performed sextant systematic biopsies, and the other performed extended 12-core systematic biopsies. A total of 550 patients were analyzed. Cases requiring systematic biopsy in combined biopsy exhibited a significant association with age ≥ 65 years (odds ratio [OR], 2.32; 95% confidence interval [CI], 1.25-4.32; = 0.008), PI-RADS score (OR, 2.32; 95% CI, 1.25-4.32; = 0.008), and the number of systematic biopsy cores (OR, 3.69; 95% CI, 2.11-6.44; < 0.001). In patients with an index lesion of PI-RADS 4, an extended 12-core systematic biopsy was required (target-negative/systematic-positive or a greater Gleason score in the systematic biopsy than in the targeted biopsy) ( < 0.001). During combined biopsy for prostate cancer in patients with PI-RADS 3 or 5, sextant systematic biopsy should be recommended over extended 12-core systematic biopsy when an effective targeted biopsy is performed.