Details

Autor(en) / Beteiligte

• Antonio Ribeiro de Oliveira
• Jr
• Leida Maria Botion
• Rachel Menezes Guerra
• Rodrigo Bastos Foscolo
• Lucas Jose Campos Machado
• Umeko Marubayashi
• Adelina Martha dos Reis
• Candido Celso Coimbra

Titel

Acute Metabolic Effects of Thiopental Anesthesia on Fed and Fasted Rats Chronically Treated With Bromocriptine

Ist Teil von

• Journal of Pharmacological Sciences, 2003-06, Vol.92 (2), p.149-152

Ort / Verlag

The Japanese Pharmacological Society

Erscheinungsjahr

2003

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• We investigated the acute effects of thiopental anesthesia (4mg/l00g, i.v.) on plasma glucose, insulin, triacylglycerol, and prolactin levels in rats treated with bromocriptine (BR) (0.4mg/100g body wt, i.p., for two weeks). Thiopental anesthesia induced a rapid increase in plasma insulin that was more pronounced in the animals treated with BR (116%, P<0.05). Thiopental anesthesia also produced a 55% decreased in plasma prolactin levels (P<0.01) in control fed rats, and a 22% reduction in plasma triacylglycerol (P<0.05) in both controls and BR-treated rats. We conclude that BR may constitute and additional sympatholytic factor in animals submiffed to thiopental anesthesia.