The New England journal of medicine, 2018-03, Vol.378 (9), p.809-818
- Annane, Djillali
- Renault, Alain
- Brun-Buisson, Christian
- Megarbane, Bruno
- Quenot, Jean-Pierre
- Siami, Shidasp
- Cariou, Alain
- Forceville, Xavier
- Schwebel, Carole
- Martin, Claude
- Timsit, Jean-François
- Misset, Benoît
- Ali Benali, Mohamed
- Colin, Gwenhael
- Souweine, Bertrand
- Asehnoune, Karim
- Mercier, Emmanuelle
- Chimot, Loïc
- Charpentier, Claire
- François, Bruno
- Boulain, Thierry
- Petitpas, Franck
- Constantin, Jean-Michel
- Dhonneur, Gilles
- Baudin, François
- Combes, Alain
- Bohé, Julien
- Loriferne, Jean-François
- Amathieu, Roland
- Cook, Fabrice
- Slama, Michel
- Leroy, Olivier
- Capellier, Gilles
- Dargent, Auguste
- Hissem, Tarik
- Maxime, Virginie
- Bellissant, Eric
2018
Details
- Autor(en) / Beteiligte
- Annane, Djillali
- Renault, Alain
- Brun-Buisson, Christian
- Megarbane, Bruno
- Quenot, Jean-Pierre
- Siami, Shidasp
- Cariou, Alain
- Forceville, Xavier
- Schwebel, Carole
- Martin, Claude
- Timsit, Jean-François
- Misset, Benoît
- Ali Benali, Mohamed
- Colin, Gwenhael
- Souweine, Bertrand
- Asehnoune, Karim
- Mercier, Emmanuelle
- Chimot, Loïc
- Charpentier, Claire
- François, Bruno
- Boulain, Thierry
- Petitpas, Franck
- Constantin, Jean-Michel
- Dhonneur, Gilles
- Baudin, François
- Combes, Alain
- Bohé, Julien
- Loriferne, Jean-François
- Amathieu, Roland
- Cook, Fabrice
- Slama, Michel
- Leroy, Olivier
- Capellier, Gilles
- Dargent, Auguste
- Hissem, Tarik
- Maxime, Virginie
- Bellissant, Eric
- Titel
- Hydrocortisone plus Fludrocortisone for Adults with Septic Shock
- Ist Teil von
- The New England journal of medicine, 2018-03, Vol.378 (9), p.809-818
- Ort / Verlag
- United States: Massachusetts Medical Society
- Erscheinungsjahr
- 2018
- Link zum Volltext
- Quelle
- Free E-Journal (出版社公開部分のみ）
- Beschreibungen/Notizen
- Septic shock is characterized by a dysregulated host response to infection and is associated with a mortality of 45 to 50%. In this multicenter, randomized, double-blind, placebo-controlled trial in 1241 patients, hydrocortisone plus fludrocortisone reduced 90-day mortality.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793, 1533-4406eISSN: 1533-4406DOI: 10.1056/NEJMoa1705716Titel-ID: cdi_liege_orbi_v2_oai_orbi_ulg_ac_be_2268_245123
- Format
- –
- Schlagworte
- Aged, Analysis, Anesthesia & intensive care, Anesthésie & soins intensifs, Anti-Inflammatory Agents - adverse effects, Anti-Inflammatory Agents - therapeutic use, Anti-Inflammatory Agents/adverse effects/therapeutic use, Blood pressure, Cause of Death, Clinical outcomes, Clinical trials, Combined Modality Therapy, Cortisone, Dosage and administration, Double-Blind Method, Drug administration, Drug therapy, Drug Therapy, Combination, Female, Fludrocortisone - adverse effects, Fludrocortisone - therapeutic use, Fludrocortisone/adverse effects/therapeutic use, Hormones, Human health sciences, Humans, Hydrocortisone, Hydrocortisone - adverse effects, Hydrocortisone - therapeutic use, Hydrocortisone/adverse effects/therapeutic use, Hyperglycemia, Infections, Investigations, Life Sciences, Male, Middle Aged, Mortality, Organ Dysfunction Scores, Recurrence, Renal Replacement Therapy, Respiration, Artificial, Safety and security measures, Sciences de la santé humaine, Sepsis, Septic shock, Shock, Septic - complications, Shock, Septic - drug therapy, Shock, Septic - mortality, Shock, Septic - therapy, Shock, Septic/complications/drug therapy/mortality/therapy, Simplified Acute Physiology Score, Survival Analysis, Treatment Outcome, Ventilation