Details

Autor(en) / Beteiligte

• Shivaraj, Yellappa
• Naveen, Malenahalli H
• Vijayakumar, Giriyapura R
• Kumar, Doyijode B. Aruna

Titel

Design, Synthesis and Antibacterial Activity Studies of Novel Quinoline Carboxamide Derivatives

Ist Teil von

• Journal of the Korean Chemical Society, 2013, Vol.57 (2), p.241-245

Erscheinungsjahr

2013

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• A series of novel quinoline-6-carboxamides and 2-chloroquinoline-4-carboxamides were synthesized by the reaction of their analogous carboxylic acids with various amine derivatives in the presence of base TEA and protecting agent BOP at room temperature. Synthesized compounds were confirmed by spectral characterization viz IR, $^1H$-NMR, and MS. Antibacterial activity carried out against Escherichia coli and Staphyllococcus aureus indicated that the synthesized compounds were active against these microorganisms.