Details

Autor(en) / Beteiligte

• Lee, Kyung-Ah
• Moon, Sun-Hee
• Kim, Kee-Tae
• Mendonca, Aubrey F
• Paik, Hyun-Dong

Titel

Antimicrobial Effects of Various Flavonoids on Escherichia coli O157:H7 Cell Growth and Lipopolysaccharide Production

Ist Teil von

• Food science and biotechnology, 2010, Vol.19 (1), p.257-261

Erscheinungsjahr

2010

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Flavonoids have biofunctional effects as antioxidant and antimicrobial agents. The objective of this study was to evaluate the bactericidal activity and antilipopolysaccharide (LPS) effects of flavonoids on Escherichia coli O157:H7. The effects of flavonoids on the growth of E. coli O157:H7 were bacteriostatic rather than bactericidal at concentrations below 200 ${\mu}m$, and there was no significant difference among the flavonoids tested (p<0.05). LPS production in E. coli O157:H7 treated with 200 ${\mu}m$ quercetin and naringenin decreased by 34.06${\pm}$1.03 and 19.90${\pm}$1.51%, respectively, relative to the control (no flavonoid). Luteolin, genkwanin, hesperetin, and apigenin caused decreases in LPS production of 69.85${\pm}$1.03, 61.18${\pm}$1.15, 60.74${\pm}$1.10, and 58.93${\pm}$0.98%, respectively, relative to the control. Based on these results, luteolin had the greater inhibitory effect on LPS production by E. coli O157:H7 than other flavonoids tested in this study.