Details

Autor(en) / Beteiligte

• 홍순복
• 김은해
• 마진열
• 은영아
• 김한섭
• 박갑주
• Hong, Soon-Bok
• Kim, Eun-Hae
• Ma, Jin-Yeul
• Eun, Young-Ah
• Kim, Han-Seob
• Park, Kap-Joo

Titel

녹혈이 Cyclophosphamide로 유도된 악성빈혈의 조혈기능 촉진에 미치는 영향

Ist Teil von

• 생약학회지, 1998, Vol.29 (4), p.283-292

Erscheinungsjahr

1998

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• The hemopoietic effects of deer blood (whole blood, blood cell, plasma, respectively) were examined using in vivo rat model. Experimental animals (Sprague-Dawley rat, male, 200 g) were divided into negative control group (injection of saline), positive control group (injection of Sipjeondaebotang) experimental groups (injection of whole blood, blood cell, plasma) and healthy control group. Cyclophosphamide(150mg/kg) was injected into experimental groups, negative and positive control group to induce bone marrow supression. After 8 days, freez dried deer blood (whole blood, blood cell, plasma respectively) and Sipjeondaebotang of 200 mg/kg in dose was administered orally into experimental groups and positive control group, once a day for 3 days (A group) and once a day for 12 days (B group) respectively. And then body weight and organ weight, biochemical profile (ALB, GOT, GPT, PRO, CRE), hematological values (WBC, RBC, HGB, HCT, MCV, MCH, MCHC, PLT) and CBC differentiation (Neutro, Lymph, Mono, Reticulo) were carried out. Finally, platelets were specially increased in the plasma treated A group and reticulocytes were specially increased in the plasma treated B group.