Details

Autor(en) / Beteiligte

• 김윤정
• Yoon Jung Kim
• 정은욱
• Eun Uk Jung
• 강명주
• Myoung Joo Kang
• 박상원
• Sang Won Park
• 최바울
• Pa Ul Choi
• 김지현
• Ji Hyun Kim
• 박성재
• Sung Jae Park
• 지삼룡
• Sam Ryong Jee
• 박은택
• Eun Taek Park
• 이연재
• Youn Jae Lee
• 이상혁
• Sang Hyuk Lee

Titel

궤양성 대장염 환자에서 발생한 대장의 원발성 소세포암 1예

Ist Teil von

• Taehan Sohwagi Naesigyŏng Hakhoe chi, 2008-01, Vol.36 (1), p.52

Ort / Verlag

대한소화기내시경학회

Erscheinungsjahr

2008

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• 위장관에 발생하는 소세포암은 발생 빈도가 낮고, 특히 대장에 발생하는 원발성 소세포암은 극히 드문것으로 보고되고 있다. 저자들은 궤양성 대장염으로 치료 받고 있던 중 2주간의 복통과 변비를 주소로 내원한 60세 여자환자에서 대장의 소세포암을 진단하고 수술과 복합항암요법을 통해 치료 중인 예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Small cell carcinoma associated with ulcerative colitis is a rare malignancy of the colon, so we report here on a case of small cell carcinoma (SCC) of the large bowel. A 60-yr-old woman had been diagnosed with ulcerative colitis about 10 years previously, and she was then continuously treated with 5-ASA. Colonoscopy was being done every two years for cancer surveillance. The last colonoscopy was done 16 months previously. At that time, colonoscopic finding was mild left side colitis. She was hospitalized because of severe abdominal pain and acute constipation that developed 2 weeks previously. During the colonoscopic examination, an obstructive mass was noted on the rectum. Pathology revealed small cell carcinoma. NSE (neuron specific enolase) and Synaptohpysin were strongly positive. Chromogranin and Cytokeratin were focally positive to a weak degree. So, the patients received a Hartmann`s operation (T-colostomy). The mass had grossly invaded the adjacent peritoneum and serosa. Therefore, only the mass was removed. She then received chemotherapy with cisplatin and irinotecan for 2 cycles. She achieved a stable state 2 months after the operation. Only a few cases of colorectal SCC associated with ulcerative colitis have been reported, and its etiology remains unknown. Thus, we report here on a small cell carcinoma arising from ulcerative colitis. Korean J Gastrointest Endosc 2008;36:52-56)