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요르단인의 HUMvWA31 , HUMTH01 , HUMF13A1 and HUMFES / FPS STR 유전자 좌위의 다형
Ist Teil von
Genes & genomics, 2001-06, Vol.23 (2), p.157
Ort / Verlag
한국유전학회
Erscheinungsjahr
2001
Beschreibungen/Notizen
DNA typing was performed on a sample population consisting of 93 unrelated Jordanians using the ABI PrismTMSTR Primer Set for PCR Amplification and Typing of HUMvWA31, HUMTH01, HUMF13A1, and HUMFES/FPS. Genotypic and allelic frequencies for the HUMvWA31, HUMTH01, HUMF13A1, and HUMFES/FPS STR loci were calculated and statistically analyzed. Genotype distribution for all four loci was in agreement with the expectations of the HWE. Our data show that the combined power of discrimination using these four loci (PD: 0.999953) is reasonably high considering the size of the Jordanian population. Allelic frequencies at the TH01 and FES/FPS loci are significantly different from those observed in African Americans as well as Hispanic Americans. This is significant in light of the fact that forensic laboratories routinely use genetic data for populations to which the individual in question may no necessarily belong. Data presented here have useful applications in forensics, clinical diagnosis and ethnogenetics.