Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist gegebenenfalls nur via VPN oder Shibboleth (DFN-AAI) möglich. mehr Informationen...
Chromosome location, genomic organization of the porcine COL10A1 gene and model structure of the NC1 domain
Ist Teil von
Cytogenetic and Genome Research, 2003-01, Vol.102 (1-4), p.173-178
Ort / Verlag
Basel, Switzerland: S. Karger AG
Erscheinungsjahr
2003
Quelle
MEDLINE
Beschreibungen/Notizen
The porcine COL10A1 gene, encoding the α1(X) chain of type X collagen, has been sequenced. The gene structure is evolutionarily conserved, consisting of three exons and two introns spanning 7100 bp. Linkage mapping localized the gene to chromosome 1, which is in agreement with human-pig homology maps. Furthermore, protein structure comparison of the functionally important carboxyl domain between species revealed that amino acid changes were few and mainly situated in loop regions.