Details

Autor(en) / Beteiligte

• Gursu, Meltem
• Ozturk, Savas
• Arici, Mustafa
• Sahin, Idris
• Gokcay Bek, Sibel
• Yilmaz, Murvet
• Koyuncu, Sumeyra
• Karahisar Sirali, Semahat
• Ural, Zeynep
• Dursun, Belda
• Yuksel, Enver
• Uzun, Sami
• Sipahi, Savaş
• Ahbap, Elbis
• Artan, Ayse Serra
• Altunoren, Orcun
• Tunca, Onur
• Ayar, Yavuz
• Gok Oguz, Ebru
• Yilmaz, Zulfukar
• Kahvecioglu, Serdar
• Asicioglu, Ebru
• Oruc, Aysegul
• Altiparmak, Mehmet Riza
• Aydin, Zeki
• Huddam, Bulent
• Dolarslan, Murside Esra
• Azak, Alper
• Bakırdogen, Serkan
• Yalcin, Ahmet Ugur
• Karadag, Serhat
• Ulu, Memnune Sena
• Gungor, Ozkan
• Ari Bakir, Elif
• Odabas, Ali Rıza
• Seyahi, Nurhan
• Yildiz, Alaattin
• Ates, Kenan

Titel

Characteristics and Survival Results of Peritoneal Dialysis Patients Suffering from COVID-19 in Turkey: A Multicenter National Study

Ist Teil von

• Kidney & blood pressure research, 2022-11, Vol.47 (10), p.605-615

Ort / Verlag

Basel, Switzerland: S. Karger AG

Erscheinungsjahr

2022

Quelle

MEDLINE

Beschreibungen/Notizen

• Introduction: We aimed to study the characteristics of peritoneal dialysis (PD) patients with coronavirus disease-19 (COVID-19), determine the short-term mortality and other medical complications, and delineate the factors associated with COVID-19 outcome. Methods: In this multicenter national study, we included PD patients with confirmed COVID-19 from 27 centers. The baseline demographic, clinical, laboratory, and radiological data and outcomes at the end of the first month were recorded. Results: We enrolled 142 COVID-19 patients (median age: 52 years). 58.2% of patients had mild disease at diagnosis. Lung involvement was detected in 60.8% of patients. Eighty-three (58.4%) patients were hospitalized, 31 (21.8%) patients were admitted to intensive care unit and 24 needed mechanical ventilation. Fifteen (10.5%) patients were switched to hemodialysis and hemodiafiltration was performed for four (2.8%) patients. Persisting pulmonary symptoms (n = 27), lower respiratory system infection (n = 12), rehospitalization for any reason (n = 24), malnutrition (n = 6), hypervolemia (n = 13), peritonitis (n = 7), ultrafiltration failure (n = 7), and in PD modality change (n = 8) were reported in survivors. Twenty-six patients (18.31%) died in the first month of diagnosis. The non-survivor group was older, comorbidities were more prevalent. Fever, dyspnea, cough, serious-vital disease at presentation, bilateral pulmonary involvement, and pleural effusion were more frequent among non-survivors. Age (OR: 1.102; 95% CI: 1.032–1.117; p: 0.004), moderate-severe clinical disease at presentation (OR: 26.825; 95% CI: 4.578–157.172; p < 0.001), and baseline CRP (OR: 1.008; 95% CI; 1,000–1.016; p: 0.040) were associated with first-month mortality in multivariate analysis. Discussion/Conclusions: Early mortality rate and medical complications are quite high in PD patients with COVID-19. Age, clinical severity of COVID-19, and baseline CRP level are the independent parameters associated with mortality.