Details

Autor(en) / Beteiligte

• Fernández-de-las-Peñas, César
• Palacios-Ceña, Domingo
• Gómez-Mayordomo, Víctor
• Palacios-Ceña, María
• Rodríguez-Jiménez, Jorge
• de-la-Llave-Rincón, Ana I.
• Velasco-Arribas, María
• Fuensalida-Novo, Stella
• Ambite-Quesada, Silvia
• Guijarro, Carlos
• Cuadrado, María L.
• Florencio, Lidiane L.
• Arias-Navalón, José A.
• Ortega-Santiago, Ricardo
• Elvira-Martínez, Carlos M.
• Molina-Trigueros, Luis J.
• Torres-Macho, Juan
• Sebastián-Viana, Tomas
• Canto-Diez, María Gabriela
• Cigarán-Méndez, Margarita
• Hernández-Barrera, Valentín
• Arendt-Nielsen, Lars

Titel

Fatigue and Dyspnoea as Main Persistent Post-COVID-19 Symptoms in Previously Hospitalized Patients: Related Functional Limitations and Disability

Ist Teil von

• Respiration, 2022-02, Vol.101 (2), p.132-141

Ort / Verlag

Basel, Switzerland: S. Karger AG

Erscheinungsjahr

2022

Quelle

MEDLINE

Beschreibungen/Notizen

• Background: Multicentre studies focussing on specific long-term post-COVID-19 symptoms are scarce. Objective: The aim of this study was to determine the levels of fatigue and dyspnoea, repercussions on daily life activities, and risk factors associated with fatigue or dyspnoea in COVID-19 survivors at long term after hospital discharge. Methods: Age, gender, height, weight, symptoms at hospitalization, pre-existing medical comorbidity, intensive care unit admission, and the presence of cardio-respiratory symptoms developed after severe acute respiratory syndrome coronavirus 2 infection were collected from patients who recovered from COVID-19 at 4 hospitals in Madrid (Spain) from March 1 to May 31, 2020 (first COVID-19 wave). The Functional Impairment Checklist was used for evaluating fatigue/dyspnoea levels and functional limitations. Results: A total of 1,142 patients (48% women, age: 61, standard deviation [SD]: 17 years) were assessed 7.0 months (SD 0.6) after hospitalization. Fatigue was present in 61% patients, dyspnoea with activity in 55%, and dyspnoea at rest in 23.5%. Only 355 (31.1%) patients did not exhibit fatigue and/or dyspnoea 7 months after hospitalization. Forty-five per cent reported functional limitations with daily living activities. Risk factors associated with fatigue and dyspnoea included female gender, number of pre-existing comorbidities, and number of symptoms at hospitalization. The number of days at hospital was a risk factor just for dyspnoea. Conclusions: Fatigue and/or dyspnoea were present in 70% of hospitalized COVID-19 survivors 7 months after discharge. In addition, 45% patients exhibited limitations on daily living activities. Being female, higher number of pre-existing medical comorbidities and number of symptoms at hospitalization were risk factors associated to fatigue/dyspnoea in COVID-19 survivors 7 months after hospitalization.