Details

Autor(en) / Beteiligte

• Olivas, Andrea D.
• Barroeta, Julieta E.
• Lastra, Ricardo R.

Titel

Role of Ancillary Techniques in Gynecologic Cytopathology Specimens

Ist Teil von

• Acta cytologica, 2020-01, Vol.64 (1-2), p.63-70

Ort / Verlag

Basel, Switzerland

Erscheinungsjahr

2020

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• The association between high-risk genotypes of human papillomavirus (hr-HPV) and cervical cancer is well established. As hr-HPV testing is rapidly becoming a part of routine cervical cancer screening, either in conjunction with cytology or as primary testing, the management of hr-HPV-positive women has to be tailored in a way that increases the detection of cervical abnormalities while decreasing unnecessary colposcopic biopsies or other invasive procedures. In this review, we discuss the overall utility and strategies of hr-HPV testing, as well as the advantages and limitations of potential triage strategies for hr-HPV-positive women, including HPV genotyping, p16/Ki-67 dual staining, and methylation assays.