Proceedings of the National Academy of Sciences - PNAS, 1991-04, Vol.88 (7), p.2697-2701
1991
Details
- Autor(en) / Beteiligte
- Titel
- Expression of a mRNA Related to c-rel and Dorsal in Early Xenopus laevis Embryos
- Ist Teil von
- Proceedings of the National Academy of Sciences - PNAS, 1991-04, Vol.88 (7), p.2697-2701
- Ort / Verlag
- Washington, DC: National Academy of Sciences of the United States of America
- Erscheinungsjahr
- 1991
- Link zum Volltext
- Quelle
- Free E-Journal (出版社公開部分のみ）
- Beschreibungen/Notizen
- We describe a Xenopus mRNA, Xrel1, that is related to the avian protooncogene c-rel, the embryonic pattern gene dorsal of Drosophila, and the mammalian transcription factor NK-κB/KBF1. The sequence of Xrel1 is homologous to the other rel-related proteins in the large amino-terminal region that defines this class of transcriptional regulators, but the carboxyl-terminal part of the protein is quite different. Xrel1 mRNA is present throughout oogenesis and during early embryogenesis at 4 x 105transcripts per oocyte or embryo. Xrel1 transcripts are present in all of the dissected parts of early embryos that we have examined. They are enriched in the animal hemisphere compared to the vegetal hemisphere of oocytes and blastulae.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0027-8424eISSN: 1091-6490DOI: 10.1073/pnas.88.7.2697Titel-ID: cdi_jstor_primary_2356252
- Format
- –
- Schlagworte
- Amino Acid Sequence, Amino acids, Animals, Base Sequence, Biological and medical sciences, Blotting, Northern, c-Rel, Cloning, Molecular, Drosophila, Eggs, Embryo, Nonmammalian - physiology, Embryonic and Fetal Development, Embryos, Female, Fundamental and applied biological sciences. Psychology, Genes. Genome, Mesoderm, Messenger RNA, Molecular and cellular biology, Molecular genetics, Molecular Sequence Data, NF-kappa B - genetics, Nucleotides, Oocytes, Oocytes - physiology, Oogenesis, Protein-Tyrosine Kinases - genetics, Proto-Oncogene Proteins - genetics, Proto-Oncogene Proteins c-rel, Restriction Mapping, RNA, RNA, Messenger - genetics, transcription factors, Xenopus laevis, Xenopus laevis - embryology, Xrel1