Details

Autor(en) / Beteiligte

• TANAKA, Nobuhisa
• JINGU, Daiki

Titel

Reference ranges for serum immunoglobulins (IgG, IgA, and IgM) in early neonatal period

Ist Teil von

• Japanese Journal of Medical Technology, 2021/07/25, Vol.70(3), pp.525-528

Ort / Verlag

Japanese Association of Medical Technologists

Erscheinungsjahr

2021

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• The levels of serum immunoglobulins vary depending on age, particularly in children. Therefore, an age-related reference range of individuals must be used when evaluating a patient’s immunoglobulin levels. We determined reference ranges for serum immunoglobulins (IgG, IgA, and IgM) in the early neonatal period (0–6 days after birth). Data were from patients in the early neonatal period admitted to our Neonatal Intensive Care Unit and Growing Care Unit. Our subjects were divided into three groups on the basis of gestational age (GA): 21–27 weeks, 28–36 weeks, and 37–42 weeks. There was a significant difference in the serum IgG level among the three groups. Thus, for IgG, considering the effect of GA is useful for estimating the reference range for infants in the early neonatal period. On the other hand, there was no correlation among the three groups in terms of serum IgA and IgM levels; thus, it was not necessary to consider the effect of GA in these groups.