Details

Autor(en) / Beteiligte

• Widmer, Andreas F.
• Colombo, Victor E.
• Gächter, André
• Thiel, Gilbert
• Zimmerli, Werner

Titel

Salmonella Infection in Total Hip Replacement: Tests to Predict the Outcome of Antimicrobial Therapy

Ist Teil von

• Scandinavian Journal of Infectious Diseases, 1990, Vol.22 (5), p.611-618

Ort / Verlag

Taylor & Francis

Erscheinungsjahr

1990

Link zum Volltext

Quelle

Taylor & Francis

Beschreibungen/Notizen

• We report a hematogenous implant infection with Salmonella dublin in a renal transplant patient with total hip replacement. A 16-month treatment with cotrimoxazole foiled, as evidenced by culture and electron microscopy, despite persisting low MIC after therapy. Data from a foreign body animal model and in vitro tests, which take into account the properties of adhering and stationary-phase bacteria, explain the failure of a long-term treatment with cotrimoxazole. The patient was subsequently cured by ciprofloxacin which was successful in these tests. No relapse was noted after a follow-up of 1 year.