Details

Autor(en) / Beteiligte

• Zuk, Peter
• Sanchez, Clarissa E.
• Kostick-Quenet, Kristin
• Muñoz, Katrina A.
• Kalwani, Lavina
• Lavingia, Richa
• Torgerson, Laura
• Sierra-Mercado, Demetrio
• Robinson, Jill O.
• Pereira, Stacey
• Outram, Simon
• Koenig, Barbara A.
• McGuire, Amy L.
• Lázaro-Muñoz, Gabriel

Titel

Researcher Views on Changes in Personality, Mood, and Behavior in Next-Generation Deep Brain Stimulation

Ist Teil von

• AJOB neuroscience, 2023-07, Vol.14 (3), p.287-299

Ort / Verlag

Philadelphia: Taylor & Francis

Erscheinungsjahr

2023

Beschreibungen/Notizen

• The literature on deep brain stimulation (DBS) and adaptive DBS (aDBS) raises concerns that these technologies may affect personality, mood, and behavior. We conducted semi-structured interviews with researchers (n = 23) involved in developing next-generation DBS systems, exploring their perspectives on ethics and policy topics including whether DBS/aDBS can cause such changes. The majority of researchers reported being aware of personality, mood, or behavioral (PMB) changes in recipients of DBS/aDBS. Researchers offered varying estimates of the frequency of PMB changes. A smaller majority reported changes in personality specifically. Some expressed reservations about the scientific status of the term 'personality,' while others used it freely. Most researchers discussed negative PMB changes, but a majority said that DBS/aDBS can also result in positive changes. Several researchers viewed positive PMB changes as part of the therapeutic goal in psychiatric applications of DBS/aDBS. Finally, several discussed potential causes of PMB changes other than the device itself.