Details

Autor(en) / Beteiligte

• Liu, Jifeng
• Liu, Feiyan
• Zhang, Nenling
• Wang, Yafeng
• Yang, Lijia
• Bi, Yuefeng
• Zhang, Yanbing
• Liu, Mengqi

Titel

Two new sesquiterpene lactones from the fruits of Illicium jiadifengpi

Ist Teil von

• Natural product research, 2016, Vol.30 (3), p.322-326

Ort / Verlag

England: Taylor & Francis

Erscheinungsjahr

2016

Link zum Volltext

Quelle

Taylor & Francis

Beschreibungen/Notizen

• Two new seco -prezizaane-type sesquiterpenes, 3,4-dehydroneomajucin (1) and 1,2,3,4-tetradehydroneomajucin (2), were isolated from the fruits of Illicium jiadifengpi . The structure of these compounds was determined using 1D and 2D NMR and ESI-MS. The isolates were evaluated for their anti-hepatitis B virus activities on the Hep G2.2.15 cell line. The inhibitory rates of compounds 1 and 2 on the HBeAg and HBsAg expression were 30.08 ± 3.09% and 11.43 ± 1.92% at a concentrations of 68.00 μM and 7.88 ± 1.21% and 16.96 ± 4.24% at a concentration of 68.50 μM, respectively.