Details

Autor(en) / Beteiligte

• Nemati Mahand, Saba
• Niknami, Niloofar
• Moghaddam, Armaghan
• Nemati Mahand, Sogand
• Salehi Moghaddam, Abolfazl
• Arjmand, Mohammad
• Alt, Franziska
• Kruppke, Benjamin
• Khonakdar, Hossein Ali

Titel

Application of stem cells, growth factors, small molecules, and biological macromolecules on nerve regeneration: a review and future direction

Ist Teil von

• International journal of polymeric materials, 2024-06, Vol.73 (9), p.817-849

Ort / Verlag

Philadelphia: Taylor & Francis

Erscheinungsjahr

2024

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The nervous system is a vital component of the human body, and its dysfunction can have fatal consequences or severe adverse effects. After significant disabling conditions, the nervous system is not able to recover damaged parts. Schwann cells are needed in a short period to regenerate nerve cells, but they do not support axonal growth-permissive phenotype. In this regard, implanting growth factors, small molecules, stem cells, and biological macromolecules in peripheral nerve injury would promote axonal outgrowth. In this review, the nervous system, related injuries, and essential factors applied for nerve regeneration are systematically highlighted.