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Machine learning sits at the core of many essential products and services at Facebook. This paper describes the hardware and software infrastructure that supports machine learning at global scale. Facebook's machine learning workloads are extremely diverse: services require many different types of models in practice. This diversity has implications at all layers in the system stack. In addition, a sizable fraction of all data stored at Facebook flows through machine learning pipelines, presenting significant challenges in delivering data to high-performance distributed training flows. Computational requirements are also intense, leveraging both GPU and CPU platforms for training and abundant CPU capacity for real-time inference. Addressing these and other emerging challenges continues to require diverse efforts that span machine learning algorithms, software, and hardware design.