Details

Autor(en) / Beteiligte

• Liu, Y.
• Shapero, A.
• Zhang, X.
• Kang, D.
• Park, J.
• Xu, L.
• Chang, K.
• Lin, H.
• Ferreri, K.
• Tai, Y. C.

Titel

MEMS for single-islet electroisletogram

Ist Teil von

• 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS), 2015, p.77-80

Ort / Verlag

IEEE

Erscheinungsjahr

2015

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• This paper reports the first MEMS device designed for in vitro measuring of electroisletogram (EIG) of individual rat islets. Using vacuum to hold an islet in proximity to a microelectrode, strong EIG signals in millivolt range are obtained, while the noise is about 100μV pk-pk. This work proves the feasibility of using MEMS and EIG for high-throughput screening, in contrast to patch-clamp measurements, of islets for transplantation to treat diabetes.