Details

Autor(en) / Beteiligte

• Carrara, S.
• Bolomey, L.
• Boero, C.
• Cavallini, A.
• Meurville, E.
• De Micheli, G.
• Jost, T. R.
• Proietti, M.
• Grassi, F.

Titel

Remote System for Monitoring Animal Models With Single-Metabolite Bio-Nano-Sensors

Ist Teil von

• IEEE sensors journal, 2013-03, Vol.13 (3), p.1018-1024

Ort / Verlag

IEEE

Erscheinungsjahr

2013

Quelle

IEEE Xplore

Beschreibungen/Notizen

• A novel system for remote monitoring of metabolism in an animal model is proposed in this paper. The system is obtained by integrating bio-nano-sensors to detect single-metabolites, an electrochemical front-end made with off-the-shelf components, a radio frequency communication sub-system, and an antenna of new design. The system has been calibrated and tested for continuous monitoring of four different metabolites: glucose, lactate, glutamate, and adenosine triphosphate. Tests using animal models (mice) have been conducted to investigate tissue inflammation induced by the implanted bio-nano-sensors. These tests confirm that our system is suitable and reliable for remote monitoring of single-metabolites in experiments with animal models.