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Cortical bone fluid flow and species transport induced by an array of blood vessels
Ist Teil von
Proceedings of 16th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 1994, Vol.2, p.1146-1147 vol.2
Ort / Verlag
IEEE
Erscheinungsjahr
1994
Quelle
IEEE Electronic Library Online
Beschreibungen/Notizen
A mathematical model is developed which describes cortical bone fluid flow and species transport in the vicinity of several in-bone vessel canals. Model simulations are qualitatively consistent with experimental observations and indicate that solute contact with the surrounding bone is approximately 85 percent complete when vessel canal radii are larger than /spl sim/1 percent of the cortex's thickness. In contrast, essentially no solute reaches the surrounding bone when radii are less than /spl sim/0.1 percent of the cortex's thickness. Implications of this prediction are discussed.