Details

Autor(en) / Beteiligte

• Rehse, S. J.
• Blanchette, E. J.

Titel

Laser-Induced Breakdown Spectroscopy for the Identification of Pathogens in Blood and Urine

Ist Teil von

• 2023 IEEE International Conference on Plasma Science (ICOPS), 2023, p.1-1

Ort / Verlag

IEEE

Erscheinungsjahr

2023

Quelle

IEEE/IET Electronic Library

Beschreibungen/Notizen

• Our group has demonstrated the ability to detect and classify bacterial cells in arbitrary fluid specimens using a centrifugation device to deposit cells on nitrocellulose filters.1 Bacterial concentrations of 11,000 CFU per laser shot were detectable using 8 mJ pulses from a 1064 nm, 9 ns Nd:YAG laser with a spot size 75 μm in diameter. A partial least squares discriminant analysis on LIBS spectra from specimens of blood and urine spiked with known bacterial pathogens possessed a 98.9% sensitivity and 100% specificity for detection in urine and a 96.3% sensitivity and 98.6% specificity for detection in blood.