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Reducing contamination while closing the gap: BASSI RF pulses in PASL
Magnetic resonance in medicine, 2006-04, Vol.55 (4), p.865-873
Warnking, Jan M.
Pike, G. Bruce
2006
Details
Autor(en) / Beteiligte
Warnking, Jan M.
Pike, G. Bruce
Titel
Reducing contamination while closing the gap: BASSI RF pulses in PASL
Ist Teil von
Magnetic resonance in medicine, 2006-04, Vol.55 (4), p.865-873
Ort / Verlag
Hoboken: Wiley Subscription Services, Inc., A Wiley Company
Erscheinungsjahr
2006
Link zum Volltext
Quelle
MEDLINE
Beschreibungen/Notizen
Bandwidth‐modulated selective saturation and inversion (BASSI) pulses are a class of frequency‐ and gradient‐modulated radiofrequency (RF) pulses, derived from the hyperbolic secant pulse by temporal variation of the bandwidth parameter. These pulses afford optimal amplitude modulation, achieving uniform and highly selective profiles at any effective flip angle. In this paper, BASSI pulses are parameterized to obtain low RF energy pulsed arterial spin labeling (PASL) label pulses with minimal contamination of static spins outside the label region and highly selective PICORE/QUIPSS II saturation pulses allowing for small label gaps. They are compared to frequency offset corrected inversion (FOCI) label pulses and sinc saturation pulses in simulations and a phantom experiment. Drawing on the outstanding selectivity of bandwidth‐modulated saturation pulses, a new noninvasive method to measure in vivo the contamination effects due to direct and indirect saturation of static spins by the label pulse is presented. In an in vivo study on four subjects, contamination effects in a QUIPSS II PASL implementation based on BASSI pulses are compared to those present in a state‐of‐the‐art Q2TIPS sequence employing a FOCI label pulse. Residual contamination in the QUIPSS II/BASSI sequence is shown to be reduced by a factor of 3, compared to the Q2TIPS/FOCI sequence. In vivo human perfusion images obtained with a label gap of only 2 mm are presented. Magn Reson Med, 2006. © 2006 Wiley‐Liss, Inc.
Sprache
Englisch
Identifikatoren
ISSN: 0740-3194
eISSN: 1522-2594
DOI: 10.1002/mrm.20843
Titel-ID: cdi_hal_primary_oai_HAL_inserm_00388986v1
Format
–
Schlagworte
adiabatic RF pulses
,
Adult
,
Bayes Theorem
,
Bioengineering
,
Blood Flow Velocity
,
Brain Mapping
,
Brain Mapping - methods
,
Cerebrovascular Circulation
,
human cerebral perfusion imaging
,
Humans
,
Imaging
,
Life Sciences
,
Magnetic Resonance Imaging
,
Magnetic Resonance Imaging - methods
,
Neurons and Cognition
,
Phantoms, Imaging
,
pulsed arterial spin labeling
,
Radio Waves
,
RF power desposition
,
Spin Labels
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