Details

Autor(en) / Beteiligte

• Fressigné, Catherine
• Jean, Alexandre
• Sanselme, Morgane
• Blanchet, Jérôme
• Rouden, Jacques
• Maddaluno, Jacques
• de Paolis, Michaël

Titel

Intra- and Intermolecular Cation–π Interactions between Onium Salts and Alkynes/Acetylene: Experimental and Theoretical Insights

Ist Teil von

• Journal of organic chemistry, 2023, Vol.88 (20), p.14494-14503

Ort / Verlag

American Chemical Society

Erscheinungsjahr

2023

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Cation–π interactions between various onium salts, alkynes, and acetylene were studied, taking into account the substituents of the triple bond, the nature of the anions, and the polarity of the solvent, through a combination of MP2 calculations and experiments. In an intramolecular setting, these data (including single-crystal X-ray crystallography) concurred with the stability of folded conformers of alkynyl onium salts, even substituted with electron-withdrawing groups. To examine the contribution of these interactions on the alkyne electronic population, a thorough in silico study was carried out using natural bonding orbital analysis of the conformers. Intramolecular interactions from sulfonium salt tethered to phenylalkyne were highlighted, as illustrated above by the computed folded conformation (MP2) along with noncovalent interaction (NCI) analysis. Furthermore, investigations of intermolecular interactions, involving acetylene or phenylacetylene with various onium ions, revealed the high energy interactions of their complexes with phenyldimethylsulfonium chloride, as illustrated above with the complex PhC≡CH/PhMe2SCl (MP2 calculations and NCI analysis).